Marmer, Robert H. & Susan Parks, Ozone Treatment in Retinitis Pigmentosa: Effect on Color Perception and Blood Gasses. Annals of Ophthalmology 30: 161-163, 1998.
For 15 consecutive days, 200 cc of blood were collected, mixed with ozone gas, and reinfused into a retinitis pigmentosa patient. An arterial PO2 blood gas and a 100 Hue Farnsworth Color Perception test were performed before and after ozone administration. An increase in the PO2 level and enhanced quality of color vision was documented. Duration of effect is estimated at four to six months. IV administration of ozone at four- to six-month intervals appears to be an effective therapy to enhance visual capabilities in RP patients.