Agrillo, Alessandro; Pierpaolo Sassano; Claudio Rinna; Paolo Priore & Giorgio Iannetti, Ozone Therapy in Extractive Surgery on Patients Treated With Biphosphonates. Journal of Craniofacial Surgery 18(5): 1068-1070, 2007.
It is certain that oral extractive surgery is a remarkable trigger to avascular osteonecrosis of the jaw in patients treated with pyrophosphate analogous. This acquisition limits the use of endo-oral surgery in those patients, even when they have already developed the lesions. In this study, we present the results obtained in a group of 15 patients deriving from a 33-patient cluster with osteonecrosis of the jaw in treatment at our department with a new protocol based on ozone therapy. The object of this article is to demonstrate how dental extraction becomes possible in a patient with avascular bisphosphonate-related jaw osteonecrosis or in those who simply received pyrophosphate analogous when proper treatment with ozone therapy has been done.